keloid相关论文
目的:探讨瘢痕疙瘩成纤维细胞对M0型巨噬细胞极化、炎症因子表达的影响及可能机制,为瘢痕疙瘩治疗的新靶点提供理论依据。方法:2020......
长期的不良饮食习惯可造成肠道菌群改变,使得内毒素/脂多糖大量生成,导致肠道黏膜通透性增加,激活大量炎症因子进入门静脉。此外,高碳......
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Compound Astragalus and Salvia Miltiorrhiza Extract suppresses cell migration of keloid fibroblasts:
Aim: To investigate the effects of Compound Astragalus and Salvia Miltiorrhiza Extract (CASE) on cell migration of keloi......
Influence of cyclinD1 targeting on cell proliferation and related signal transduction pathway in kel
To investigate the effect of sequence-specific small interfering RNA (siRNA)on suppressing cyclinD 1 expression and prol......
Compound Astragalus and Salvia Miltiorrhiza Extract Suppresses Migration of Keloid Fibroblasts Invol
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Objective To discuss the width frontalis muscle flap suspension in treatment of severe blepharoptosis effect.Method 52 e......
Influence of RNA Interference Mediated Cyclin D1 Gene Silencing on The Proliferation and G1 Phase Re
In order to investigate the effect of sequence-specific small interfering RNA on suppressing cyclin D1 expression and pr......
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Objectives:Mechanistic target of rapamycin (mTOR) activation has been identified in keloid.This study aimed to identify ......
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皮肤损伤后的异常愈合会导致病理性瘢痕的产生。病理性瘢痕的出现不仅影响美观,严重时还会造成心理和生理功能障碍。病理性瘢痕的机......
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目的:探讨切除耳部瘢痕疙瘩的手术方法和及时放疗联合应用的疗效.方法:对1 34例耳部瘢痕疙瘩病例采取不同的手术方法,特别对较大的......
瘢痕疙瘩是机体皮肤受到创伤后在修复过程中形成的一种病理性瘢痕,其形成机制尚不清楚,目前其治疗方法很多,国内外学者对此进行了大量......
[摘要]目的:探讨黏着斑激酶相关非激酶(facol adhesion kinase-ralated nonkinase,FRNK)在瘢痕疙瘩组织中的表达及意义。方法:利用Weste......
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病理性瘢痕主要包括增生性瘢痕和瘢痕疙瘩,成纤维细胞是其发生、发展的主体细胞.正常皮肤、增生性瘢痕真皮浅层和真皮深层的成纤维......
瘢痕疙瘩形成是一个复杂的生物学过程,指在皮肤创伤后局部结缔组织过度增生且超出原有损害范围。该病发病机制不清,可能与常染色体显......
瘢痕疙瘩的发病机制一直未完全揭示,至今仍无一个令人十分满意的治疗方案。由于患者个体之间的差异性,以及不同治疗方案之间的优势和......
瘢痕疙瘩( KD)是病理性瘢痕的一种,其发病机制十分复杂,目前对其治疗仍无突破性进展。 KD在各人种间的遗传异质性、易感变异效应各不相......
Reconstruction of a large defect of the female chest following keloid excision with use of the rectu
Aim: This study aimed to investigate the efficacy of the myocutaneous flap of the rectus abdominis in the surgical treat......
目的 观察曲安奈德联合γ干扰素治疗瘢痕疙瘩的临床效果.方法 将66例瘢痕疙瘩患者随机分成实验组及对照组,分别给予曲安奈德联合γ......
目的 探讨实时荧光定量逆转录聚合酶链反应(RT- PCR)法检测富含半胱氨酸的酸性分泌糖蛋白(secreted protein,acidic and rich in c......
碱性成纤维细胞生长因子(basicfibroblastgrowthfac-tor,bFGF)和血管内皮生长因子(vascularendothelialgrowthfactor,VEGF)或血管通透因子(vascularpermeabil-ityfac...
Basic fibroblast growth factor (bFGF) and vascular endothelia......
目的:探讨手术切除、曲安奈德注射联合90Sr-90Y敷贴治疗瘢痕疙瘩的疗效.方法:将61例瘢痕疙瘩患者随机分为试验组(31例)和对照组(30......
目的:提高对并发表皮囊肿的瘢痕疙瘩的临床认识,为改进其治疗方法提供依据.方法:回顾性分析75例并发表皮囊肿的瘢痕疙瘩患者的临床......
Treatment of Keloids in A Child with Surgery Alone: Clinical Application of the LBD Suturing Techniq
Keloids are fibroproliferative disorders that can result from cutaneous injuries to the reticular dermis. Recurrence rat......
目的探讨过氧化物酶体增殖物激活受体γ(peroxisome proliferator activated receptorγ,PPAR-γ)在瘢痕疙瘩组织中的表达及其意义。......
目的 观察瘢痕组织瓣修复术联合5%咪喹莫特乳膏治疗耳部瘢痕疙瘩的临床疗效和安全性.方法 将入选的75例耳部瘢痕疙瘩患者按随机数字......
目的 观察耳部瘢痕疙瘩术前注射和核心切除术联合术后放疗的临床疗效和安全性.方法 将入选的40例耳部瘢痕疙瘩患者随机分为两组,各......
瘢痕疙瘩是一种以皮肤结缔组织增生和侵袭性生长为主要特征的病理性瘢痕。多在外伤、炎症、手术后形成,好发于胸前、肩胛部、耳垂......
患者男,22岁,前胸、双上臂外侧起谷粒至蚕豆大的丘疹3年余.皮肤科情况:前胸、双上臂外侧可见散在对称性暗红色丘疹.皮肤组织病理示......
瘢痕疙瘩是一种皮肤创伤愈合过程中成纤维细胞异常增殖所导致的皮肤良性肿瘤,亚裔人群的发生率约为0.15%,尚无根治方法.激光治疗是......
,The effect of surgical skin tension reduction combined with early electronic line irradiation on ke
Background Median stemotomy remains the preferred technique in open heart surgery.The middle part of the chest is a pred......
,Comparative study of microRNA profiling in keloid fibroblast and annotation of differential express
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Keloids (KDs) and hypertrophic scars (HSs),two forms of pathological scars,seriously affect the physical and psychologic......
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目的探讨黄芩素对人体瘢痕疙瘩成纤维细胞在增殖、凋亡的影响,为临床瘢痕疙瘩的治疗提供实验基础。方法 MTT法测定黄芩素干预后瘢......
目的:探讨热休克蛋白47( HSP 47)在瘢痕疙瘩组织中的表达及与Ⅰ型、Ⅲ型胶原的相关性。方法采用免疫组织化学染色方法检测21例(瘢痕......
目的 研究确定高压氧治疗对瘢痕疙瘩放疗切除后创面皮片移植成活的影响.方法 对25例胸前瘢痕疙瘩患者行瘢痕疙瘩预放疗和病变切除......
Blocking transforming growth factor- receptor signaling down-regulates transforming growth factor-β1
Objective: To study transforming growth factor-β1(TGF-β1) autoproduction in keloid fibroblasts and theregulation effec......
Development of gene microarray in screening differently expressed genes in keloid and normal-control
Background Keloid is an intricate lesion that is probably regulated by many genes. In this study, the authors used the t......
Transforming growth factor-β1 phage model peptides isolated from a phage display 7-mer peptide libra
Background Transforming growth factor-β1 (TGF-β1) is known to have a role in keloid formation through the activation o......
Objective To investigate the inhibitory effect of photodynamic on keloid by observing the changes of various indicators ......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 研究瘢痕疙瘩组织中生存素、血管内皮生长因子(VEGF)和Caspase-3的表达及相关性.方法 采用RT-PCR和免疫组化方法分别检测生存......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......